Harry J M Groen Selected Research

2',2'-difluoro-2'-deoxyuridine

6/2010	Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.
6/2010	Gemcitabine and epirubicin plasma concentration-related excretion in saliva in patients with non-small cell lung cancer.

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Harry J M Groen Research Topics

Disease

75	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 11/2002
55	Neoplasms (Cancer) 03/2022 - 02/2002
26	Lung Neoplasms (Lung Cancer) 01/2022 - 05/2004
16	Disease Progression 02/2021 - 04/2009
11	Neoplasm Metastasis (Metastasis) 01/2021 - 02/2003
9	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 03/2010
7	Brain Neoplasms (Brain Tumor) 01/2022 - 01/2016
5	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2021 - 06/2006
4	Emphysema 12/2022 - 02/2014
4	Circulating Neoplastic Cells 12/2019 - 07/2015
4	Hypoxia (Hypoxemia) 01/2017 - 12/2012
3	Adenocarcinoma of Lung 11/2021 - 01/2016
3	Fatigue 01/2021 - 11/2017
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 05/2013
3	Pain (Aches) 01/2021 - 02/2013
2	Sarcoma (Soft Tissue Sarcoma) 04/2021 - 08/2013
2	Vomiting 02/2021 - 10/2017
2	Diarrhea 02/2021 - 11/2017
2	Malignant Mesothelioma 01/2021 - 05/2013
2	Neutropenia 01/2021 - 01/2019
2	Thrombocytopenia (Thrombopenia) 01/2019 - 08/2004
2	Adenocarcinoma 01/2018 - 01/2011
2	Mesothelioma 01/2017 - 05/2013
2	Pneumonia (Pneumonitis) 06/2005 - 05/2004
2	Radiation Pneumonitis 05/2004 - 07/2003
1	Asthma (Bronchial Asthma) 01/2022
1	Leukopenia 10/2021
1	Hyperglycemia 02/2021
1	Asthenia 01/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Cough 01/2021
1	Infections 01/2021
1	Pleural Effusion (Pleural Effusions) 10/2020
1	Prostatic Neoplasms (Prostate Cancer) 01/2020

Drug/Important Bio-Agent (IBA)

11	Biomarkers (Surrogate Marker)IBA 01/2022 - 08/2005
11	ErbB Receptors (EGF Receptor)IBA 01/2022 - 06/2010
11	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2021 - 06/2010
10	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 08/2004
9	PlatinumIBA 02/2021 - 06/2002
8	Proteins (Proteins, Gene)FDA Link 04/2021 - 11/2002
8	Gemcitabine FDA Link 02/2021 - 07/2003
7	DNA (Deoxyribonucleic Acid)IBA 03/2022 - 01/2017
7	Tyrosine Kinase InhibitorsIBA 01/2022 - 08/2013
7	CrizotinibIBA 01/2020 - 02/2015
6	Pemetrexed (MTA)FDA Link 02/2021 - 04/2009
6	Bevacizumab (Avastin)FDA Link 01/2019 - 01/2011
6	Pharmaceutical PreparationsIBA 10/2018 - 06/2002
5	Circulating Tumor DNAIBA 01/2022 - 10/2018
5	Docetaxel (Taxotere)FDA Link 10/2021 - 08/2004
5	Paclitaxel (Taxol)FDA LinkGeneric 02/2021 - 11/2007
5	AfatinibIBA 11/2020 - 09/2014
5	Cisplatin (Platino)FDA LinkGeneric 11/2017 - 06/2002
4	Anaplastic Lymphoma KinaseIBA 01/2022 - 02/2015
4	Etoposide (VP 16)FDA LinkGeneric 01/2021 - 11/2007
4	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021 - 04/2006
4	Gefitinib (Iressa)FDA Link 11/2020 - 09/2014
4	dabrafenibIBA 01/2020 - 01/2016
4	Phosphotransferases (Kinase)IBA 01/2017 - 06/2010
3	Tobacco Smoke Pollution (Passive Smoking)IBA 12/2022 - 04/2020
3	RNA (Ribonucleic Acid)IBA 03/2022 - 01/2015
3	Immune Checkpoint InhibitorsIBA 11/2021 - 12/2018
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2011
3	Cell-Free Nucleic AcidsIBA 05/2020 - 01/2015
3	trametinibIBA 01/2020 - 07/2016
3	RadiopharmaceuticalsIBA 01/2017 - 02/2002
3	CalciumIBA 01/2015 - 12/2010
2	ORALIT (ORS)IBA 01/2022 - 04/2020
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021 - 01/2019
2	veliparibIBA 01/2021 - 01/2019
2	Formaldehyde (Formol)FDA Link 10/2020 - 08/2013
2	ParaffinIBA 10/2020 - 08/2013
2	osimertinibIBA 02/2020 - 01/2020
2	brigatinibIBA 01/2020 - 08/2017
2	LigandsIBA 12/2018 - 08/2003
2	Epithelial Cell Adhesion MoleculeIBA 10/2018 - 07/2015
2	Cetuximab (Erbitux)FDA Link 11/2017 - 09/2014
2	GoldIBA 01/2016 - 01/2013
2	fluoroazomycin arabinosideIBA 11/2014 - 08/2013
2	Messenger RNA (mRNA)IBA 01/2014 - 09/2013
2	Sorafenib (BAY 43-9006)FDA Link 02/2013 - 06/2010
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2013 - 03/2010
2	Angiogenesis InhibitorsIBA 01/2011 - 08/2005
2	Epirubicin (Ellence)FDA LinkGeneric 06/2010 - 05/2004
2	2',2'-difluoro-2'-deoxyuridineIBA 06/2010 - 06/2010
1	AsbestosIBA 01/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 04/2021
1	erythromycin propionate-N-acetylcysteinateIBA 04/2021
1	rociletinibIBA 02/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	FluorineIBA 01/2021
1	AntibodiesIBA 06/2020
1	Citric Acid (Citrate)FDA LinkGeneric 05/2020
1	Analgesics (Analgesic Drugs)IBA 01/2020

Therapy/Procedure

29	Therapeutics 01/2022 - 12/2003
20	Drug Therapy (Chemotherapy) 01/2022 - 12/2003
14	Radiotherapy 01/2021 - 07/2003
5	Immunotherapy 01/2022 - 01/2017
4	Cranial Irradiation 01/2022 - 10/2018
3	Thoracotomy 02/2013 - 04/2006
2	Adjuvant Chemotherapy 01/2019 - 02/2013